Preheat the oven to 375 degrees F (190 degrees C).
Trim ends off Brussels sprouts. Quarter large ones and halve smaller ones. Place in a large bowl; drizzle with olive oil and mix well. Pour onto a rimmed baking sheet. Sprinkle with garlic powder and seasoned salt.
Bake in the preheated oven until tender, 30 to 45 minutes.
