Blend tofu in a blender until creamy. Add pumpkin, maple syrup, and cinnamon; blend until desired consistency is reached. Refrigerate.
Preheat oven to 350 degrees F (175 degrees C).
Mix flour, baking powder, and baking soda together in a large bowl. Add margarine and soy milk; stir to incorporate. Press dough into the bottom and sides of a pie pan.
Bake in the preheated oven for 20 minutes.
Remove crust from oven. Pour in refrigerated filling; return pie to the oven.